Open SBIR and STTR solicitations
The Small Business Innovation Research and Small Business Technology Transfer programs are the main route to non-dilutive federal funding for small companies doing research. Eleven agencies participate, each with its own priorities, cycles and topic lists.
The thing worth knowing when reading a list like this: the closing date is the least important column. What matters is whether your work answers the topic as written, and that question is best settled with the program officer before you write anything.
7 opportunities
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation
U.S. National Science Foundation26-511
Closes 40 days left
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
National Institutes of HealthPA-27-102
Closes 192 days left
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
National Institutes of HealthPA-27-100
Closes 192 days left
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
National Institutes of HealthPAR-27-098
Closes 923 days left
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
National Institutes of HealthPA-27-101
Closes 923 days left
NIEHS Worker Training Program’s SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)
National Institutes of HealthTEMP-30794
No fixed deadline
Forecast to Publish a Notice of Funding Opportunity for SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)
National Institutes of HealthFOR-CA-25-086
No fixed deadline
Data from Grants.gov and SBIR.gov, refreshed daily. Listings link to the official notice, which is always authoritative — check dates and eligibility there before relying on anything here.